NST-628

Non Chimik:

3-[[3-fluoro-2-(methylsulfamoylamino)pyridin-4-yl]methyl]-7-(3-fluoropyridin-2-yl)oxy-4-methylchromen-2-one

Kòd SMILES:

FC1=C(OC2=CC=C(C(C)=C(CC3=C(F))C(NS(NC)(=O)=O)=NC=C3)C(O4)=O)C4= C2)N=CC=C1

Kòd InChi:

InChI=1S/C22H18F2N4O5S/c1-12-15-6-5-14(32-21-17(23)4-3-8-27-21)11-18(15)33-22(29)16( 12)10-13-7-9-26-20(19(13)24)28-34(30,31)25-2/h3-9,11,25H,10H2,1-2H3,(H,26 ,28)

InChi kle:

YQSZJOABXRROQR-UHFFFAOYSA-N

Mot:

3002056-30-3；CAS:3002056-30-3；CAS:3002056-30-3；NST-628；NST628；NST 628

Solibilite: 

Depo:Sèk, nwa ak nan 0 -4 C pou kout tèm (jou a semèn) oswa -20 C pou tèm long (mwa a ane).

Deskripsyon:

NST-628 se yon jèl molekilè MAPK ak pèmeyabilite baryè san-sèvo, ki ka anpeche fosforilasyon RAF ak aktivasyon MEK.

Sib: RAF fosforilasyon ak MEK