Luxdegalutamid; ARV-766

Luxdegalutamid; ARV-766
  • Non:4-(4-((1-(4-(((1r,3r))-3-(4-cyano-3-methoxyphenoxy)-2,2,4,4-tetramethylcyclobutyl) carbamoyl)phenyl)piperidin-4- yl)methyl)piperazin-1-yl)-N-((S)-2,6-dioxopiperidin-3-yl)-2-fluorobenzamid
  • Nimewo katalòg:CPD115335
  • Nimewo CAS:2750830-09-0
  • Pwa molekilè:807,95
  • Fòmil chimik:C45 H54 F N7 O6
  • Pou rechèch syantifik sèlman, pa pou pasyan yo.

    Pwodwi detay

    Tags pwodwi

    Gwosè pake Disponibilite Pri (USD)

    Non Chimik:

    4-(4-((1-(4-(((1r,3r))-3-(4-cyano-3-methoxyphenoxy)-2,2,4,4-tetramethylcyclobutyl) carbamoyl)phenyl)piperidin-4- yl)methyl)piperazin-1-yl)-N-((S)-2,6-dioxopiperidin-3-yl)-2-fluorobenzamid

    Kòd SMILES:

    CC1(C)[C@H](NC(C2=CC=C(N3CCC(CN4CCN(C5=CC(F))=C(C(N[C@@H]6C(=O)NC(=O))) CC6)=O)C=C5)CC4)CC3)C=C2)=O)C(C)(C)[C@H]1OC1=CC(OC)=C(C#N)C=C1

    Kòd InChi:

    InChI=1S/C45H54FN7O6/c1-44(2)42(45(3,4)43(44)59-33-12-8-30(26-47)37(25-33)5 8-5)50-39(55)29-6-9-31(10-7-29)52-18-16-28(17-19-52)27-51-20-22-53(23- 21-51) 32-11-13-34(35(46)24-32)40(56)48-36-14-15-38(54)49-41(36)57/h6-13,24-25,28, 36,42-43H,14-23,27H2,1-5H3,(H,48,56)(H,50,55)(H,49,54,57)/t36-,42-,43-/m0 /s1

    InChi kle:

    RDPPBRKNBBXPNZ-FMPIRMQTSA-N

    Mot:

    2750830-09-0;CAS:2750830-09-0;CAS:2750830-09-0;ARV766; ARV 766; ARV-766; GTPL12624; luxdegalutamid

    Solibilite: 

    Depo:Sèk, nwa ak nan 0 - 4 C pou kout tèm (jou a semèn) oswa -20 C pou tèm long (mwa a ane).

    Deskripsyon:

    Luxdegalutamide (ARV-766) se yon oralman efikas idroliz pwoteyin vize chimerik (PROTAC) vize reseptè androjèn (AR), ki ka degrade mutan ki gen rapò ak rezistans AR.

    Sib: AR




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