OTS964
Pwodwi detay
Tags pwodwi
Gwosè pake | Disponibilite | Pri (USD) |
1g | Nan Stock | 1750 |
Plis gwosè | Jwenn Quotes | Jwenn Quotes |
Non Chimik:
(R)-9-(4-(1-(dimethylamino)propan-2-yl)phenyl)-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one
Kòd SMILES:
[H]Cl.O=C1NC2=C(C(C3=CC=C([C@@H](C)CN(C)C)C=C3)=C(O)C=C2C)C4=C1SC =C4
Kòd InChi:
InChI=1S/C23H24N2O2S.ClH/c1-13-11-18(26)19(16-7-5-15(6-8-16)14(2)12-25(3)4)20-17- 9-10-28-22(17)23(27)24-21(13)20;/h5-11,14,26H,12H2,1-4H3,(H,24,27);1H/t14-; /m0./s1
InChi kle:
YHPWOYBWUWSJDW-UQKRIMTDSA-N
Mot:
OTS 964, OTS-964, OTS964, 1338545-07-5
Solibilite:Soluble nan DMSO
Depo:0 - 4 ° C pou kout tèm (jou a semèn), oswa -20 ° C pou tèm long (mwa)
Deskripsyon:
OTS964 se yon inibitè nan lymphokine-aktive asasen T selil ki soti nan pwoteyin kinaz (TOPK; IC50 = 28 nM). Li espesyalman bloke sitokinèz, ki mennen nan apoptoz, nan yon pakèt selil kansè. OTS964 pwovoke apoptoz nan selil kansè nan poumon imen nan xenografts sourit.
Sib: TOPK