AMG-510
Pwodwi detay
Tags pwodwi
| Gwosè pake | Disponibilite | Pri (USD) |
| 1g | nan stock | 1300 |
| 5g | nan stock | 6000 |
| 10g | nan stock | 10500 |
Non Chimik:
4-((S)-4-acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl )pirido[2,3-d]pirimidin-2(1H)-yon sèl
Kòd SMILES:
O=C(C=C)N1C[C@H](C)N(C2=NC(N(C3=C(C)C=CN=C3C(C)C)C4=C2C=C(F)C) (C5=C(O)C=CC=C5F)=N4)=O)CC1
Kòd InChi:
InChI=1S/C30H30F2N6O3/c1-6-23(40)36-12-13-37(18(5)15-36)28-19-14-21(32)26(24-20(31)8- 7-9-22(24)39)34 -29(19)38(30(41)35-28)27-17(4)10-11-33-25(27)16(2)3/h6-11,14,16,18,39H,1 ,12-13,15H2,2-5H3/t18-/m0/s1
InChi kle:
NXQKSXLFSAEQCZ-SFHVURJKSA-N
Mot:
AMG-510; AMG 510; AMG510
Solibilite:
Depo:
Deskripsyon:
AMG-510 se yon inibitè ki pisan KRAS G12C kovalan. AMG-510 seleksyone vize mutan KRAS p.G12C, swa nan nivo ADN, RNA oswa pwoteyin, epi li anpeche, atravè yon fason ki poko klè, ekspresyon ak/oswa siyal selil timè atravè mutan KRAS p.G12C. Sa a ka anpeche kwasans nan selil timè ki eksprime KRAS p.G12C
Sib: KRAS
