STING agonist-4

Inoa Kimia:

1,1'-(butane-1,4-diyl)bis(2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-1H-benzo[d]imidazole-5-carboxamide)

SMILES Code:

O=C(C1=CC=C2N(CCCCN3C(NC(C4=CC(C)=NN4CC)=O)=NC5=CC(C(N)=O)=CC=C35)C(NC(C6=CC (C)=NN6CC)=O)=NC2=C1)N

Code InChi:

InChI=1S/C34H38N12O4/c1-5-45-27(15-19(3)41-45)31(49)39-33-37-23-17-21(29(35)47)9-11- 25(23)43(33)13-7-8-14-44-26-12-10-22(30(36)48)18-24(26)38-34(44)40-32(50) 28-16-20(4)42-46(28)6-2/h9-12,15-18H,5-8,13-14H2,1-4H3,(H2,35,47)(H2,36, 48)(H,37,39,49)(H,38,40,50)

Ki InChi:

ICZSAXDKFXTSGL-UHFFFAOYSA-N

Hua'ōlelo:

Hiki ke hoʻoheheʻe: 

Waihona: 

wehewehe:

ʻO STING agonist-4 kahi mea hoʻoulu i ka Interferon Genes (STING) receptor agonist me kahi mea paʻa paʻa (IC50) o 20 nM. ʻO ka STING agonist-4 kahi pūhui amidobenzimidazole (ABZI) pili pili like ʻelua e hana i nā ABZI i hoʻopili ʻia (diABZIs) me ka hoʻonui ʻia ʻana o ka hoʻopaʻa ʻana iā STING a me ka hana kelepona.

Pahuhopu: STING