STING

CAT # Inoa Huahana wehewehe
CPD101235 diABZI STING agonist-1 trihydrochloride ʻO diABZI STING agonist-1 (trihydrochloride) he mea hoʻoulu koho o nā genes interferon (STING) receptor agonist, me nā EC50 o 130, 186 nM no ke kanaka a me ka ʻiole, kēlā me kēia.
CPD101234 diABZI STING agonist-1 (Tautomerism) ʻO diABZI STING agonist-1 Tautomerism (compound 3) he mea hoʻoulu koho o nā genes interferon (STING) receptor agonist, me nā EC50 o 130, 186 nM no ke kanaka a me ka ʻiole, kēlā me kēia.
CPD101233 diABZI STING agonist-1 ʻO diABZI STING agonist-1 kahi mea hoʻoulu koho o nā genes interferon (STING) receptor agonist, me EC50s o 130, 186 nM no ke kanaka a me ka ʻiole, kēlā me kēia.
CPD101232 STING agonist-4 ʻO STING agonist-4 kahi mea hoʻoulu i ka Interferon Genes (STING) receptor agonist me kahi mea paʻa paʻa (IC50) o 20 nM. ʻO ka STING agonist-4 kahi pūhui amidobenzimidazole (ABZI) pili pili like ʻelua e hana i nā ABZI i hoʻopili ʻia (diABZIs) me ka hoʻonui ʻia ʻana o ka hoʻopaʻa ʻana iā STING a me ka hana kelepona.
CPD101231 STING agonist-3 ʻO STING agonist-3, i unuhi ʻia mai ka patent WO2017175147A1 (laʻana 10), he mea koho a me ka non-nucleotide liʻiliʻi STING agonist me ka pEC50 a me ka pIC50 o 7.5 a me 9.5. Loaʻa i ka STING agonist-3 ka hopena anti-tumor lōʻihi a hiki ke hoʻomaikaʻi i ka mālama ʻana i ka maʻi kanesa
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