STING agonist-3

STING agonist-3
  • inoa:STING agonist-3
  • Helu helu:CPD101231
  • Helu CAS.:2138299-29-1
  • Kaumaha Molekala:750.8
  • ʻO ke kumu hoʻohālike kimemika:C37 H42 N12 O6
  • No ka noiʻi ʻepekema wale nō, ʻaʻole no nā maʻi.

    Huahana Huahana

    Huahana Huahana

    Nui Puke Loaʻa Kumukuai (USD)

    Inoa Kimia:

    (E)-1-(4-(5-carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-1H-benzo[d]imidazol-1-yl)akā-2- en-1- yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-(3-hydroxypropoxy)-1H-benzo[d]imidazole-5-carboxamide

    SMILES Code:

    O=C(N)C1=CC=C(N(C(NC(C2=CC(C)=NN2CC)=O)=N3)C/C=C/CN4C5=C(N=C4NC(C6=CC) (C)=NN6CC)=O)C=C(C(N)=O)C=C5OCCCO)C3=C1

    Code InChi:

    InChI=1S/C37H42N12O6/c1-5-48-28(16-21(3)44-48)34(53)42-36-40-25-18-23(3 2(38)51)10-11-27(25)46(36)12-7-8-13-47-31-26(19-24(33(39)52)20-30(31)55- 15-9-14-50)41-37(47)43-35(54)29-17-22(4)45-49(29)6-2/h7-8,10-11,16-20, 50 H,5-6,9,12-15H2,1-4H3,(H2,38,51)(H2,39,52)(H,40,42,53)(H,41,43,54)/b8 -7+

    Ki InChi:

    VHCDRDBBENBVEK-BQYQJAHWSA-N

    Hua'ōlelo:

    Hiki ke hoʻoheheʻe: 

    Waihona: 

    wehewehe:

    ʻO STING agonist-3, i unuhi ʻia mai ka patent WO2017175147A1 (laʻana 10), he mea koho a me ka non-nucleotide liʻiliʻi STING agonist me ka pEC50 a me ka pIC50 o 7.5 a me 9.5. Loaʻa i ka STING agonist-3 ka hopena anti-tumor lōʻihi a hiki ke hoʻomaikaʻi i ka mālama ʻana i ka maʻi kanesa

    Pahuhopu: STING


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