EAI-045
Huahana Huahana
Huahana Huahana
Nui Puke | Loaʻa | Kumukuai (USD) |
Inoa Kimia:
2-(5-fluoro-2-hydroxyphenyl)-2-(3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide
SMILES Code:
O=C(NC1=NC=CS1)C(C2=CC(F)=CC=C2O)N3CC4=C(C=CC=C4)C3=O
Code InChi:
InChI=1S/C19H14FN3O3S/c20-12-5-6-15(24)14(9-12)16(17(25)22-19-21-7-8-27-19)23-10-11- 3-1-2-4-13(11)18(23)26/h1-9,16,24H,10H2,(H,21,22,25)
Ki InChi:
YTUFHOKUFOQRDF-UHFFFAOYSA-N
Hua'ōlelo:
EAI-045, EAI045, EAI 045, 1942114-09-1
Hiki ke hoʻoheheʻe:Hiki ke hoʻoheheʻe ʻia ma DMSO
Waihona:0 - 4°C no ka wā pōkole (nā lā i nā pule), a i ʻole -20°C no ka wā lōʻihi (mau mahina)
wehewehe:
ʻO EAI045 he mea hoʻohana ikaika a koho EGFR. Kuhi ʻo EAI045 i nā mutants EGFR kūpaʻa i ka lāʻau akā mālama i ka ʻano ʻano ʻāhiu. EAI045 inhibits L858R/T790M-mutant EGFR me ka haʻahaʻa-nanomolar potency i biochemical assays.
Pahuhopu: EGFR