Saukewa: ARS-1620
Cikakken Bayani
Tags samfurin
| Girman Kunshin | samuwa | Farashin (USD) |
| 100mg | A Stock | 800 |
| 500mg | A Stock | 1500 |
| 1g | A Stock | 2000 |
| Ƙarin Girman Girma | Samu Magana | Samu Magana |
Sunan Sinadari:
(S)-1-(4- (6-chloro-8-fluoro-7--2-fluoro-6-hydroxyphenyl)quinazolin-4-yl) piperazin-1-yl) prop-2-en-1-one
Lambar SMILES:
C=CC(=O)N1CCN(CC1)C2=C3C=C(C(=C4C(=O)C=CC=C4F)C(=C3NC=N2)F)Cl
Lambar InChi:
InChi=1S/C21H17ClF2N4O2/c1-2-16(30)27-6-8-28(9-7-27)21-12-10-13(22)17(19(24)20(12)25- 11-26-21) 18-14 (23)4-3-5-15(18)29/h2-5,10-11,29H,1,6-9H2
InChi Key:
QIQWMIZVWVSRAS-UHFFFAOYSA-N
Mabuɗin kalma:
ARS-1620, KRAS G12C, NSCLC, ARS1620, ARS 1620, KRASG12C, 1698055-85-4
Solubility:Mai narkewa a cikin DMSO
Ajiya:0 - 4 ° C na gajeren lokaci (kwanaki zuwa makonni), ko -20 ° C na dogon lokaci (watanni)
Bayani:
ARS-1620 prodrug ne da aka ƙera daga ARS-853, wanda shine mai hanawa S-IIP G12C mai ƙarfi da zaɓi. Ana tsammanin ARS-1620 zai zama dabarun warkewa don p.G12C KRAS mutant cancers.
Manufar: KRAS (K-Ras G12C)
