Ziftomenib;KO539

Ainm:(S)-4-Methyl-5-((4-((2-(methylamino))-6-(2,2,2-trifluoroethyl)thieno(2,3-d)pyrimidin-4-il)amino)piperidin -1-il) methyl)-1-(2-(4-(methylsulfonyl) piperazin-1-yl)propyl)-1H-indole-2-carbonitrile

Àireamh catalog:CPD113642

Àireamh CAS:2134675-36-6

Cuideam moileciuil:717.87

Foirmle Ceimigeach:C33 H42 F3 N9 O2 S2

Airson rannsachadh saidheansail a-mhàin, chan ann airson euslaintich.

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Mion-fhiosrachadh toraidh

Bathar Tags

Meud pacaid	Ri fhaotainn	Prìs (USD)
0.1G	Anns a’ bhùth	650
0.5G	Anns a’ bhùth	970
1G	Anns a’ bhùth	1350

Ainm Ceimigeach:

(S)-4-Methyl-5-((4-((2-(methylamino))-6-(2,2,2-trifluoroethyl)thieno(2,3-d)pyrimidin-4-il)amino)piperidin -1-il) methyl)-1-(2-(4-(methylsulfonyl) piperazin-1-yl)propyl)-1H-indole-2-carbonitrile

Còd SMILES:

N#CC(N1C[C@@H](N2CCN(S(=O)(C)=O)CC2)C)=CC3=C1C=CC(CN4CCC(NC5=C(C=C(CC(F)) (F)F)S6)C6=NC(NC)=N5)CC4)=C3C

Còd InChi:

InChI=1S/C33H42F3N9O2S2/c1-21(43-11-13-44(14-12-43)49(4,46)47)19-45-25(18-37)15-27-22(2) 23(5-6-29(27)45)20-42-9-7-24(8-10-42)39-30-28-16-26(17-33(34,35)36)48- 31(28)41-32(38-3)40-30/h5-6,15-16,21,24H,7-14,17,19-20H2,1-4H3,(H2,38,39,40 ,41)/t21-/m0/s1

iuchair InChi:

BGGALFIXXQOTPY-NRFANRHFSA-N

Facal-luirg:

2134675-36-6 ； CAS: 2134675-36-6 ； CAS: 2134675-36-6 ；Ziftomenib; KO539; KO 539; KO-539

Solubility:Gus a dhearbhadh

Stòradh:Tioram, dorcha agus aig 0 - 4 C airson geàrr-ùine (làithean gu seachdainean) no -20 C airson ùine fhada (mìosan gu bliadhnaichean).

Tuairisgeul:

Tha Ziftomenib (KO-539) na neach-bacadh air eadar-obrachadh menin MLL le gnìomhachd beòil.

Targaid: menin-MLL

Roimhe: 4,6-dichloro-5-fluoro-2-Methanesulfonyl-pyriMidine

Air adhart: N-Methyl-5-(piperazin-1-yl) picolinamide hydrochloride