Tavapadon

Ainm Ceimigeach:

1,5-dimethyl-6-[2-methyl-4-[3-(trifluoromethyl)pyridin-2-yl]oxyphenyl]pyrimidine-2,4-dione

Còd SMILES:

O=C1NC(C(C)=C(C2=CC=C(OC3=NC=CC=C3C(F)(F)F)C=C2C)N1C))=O

Còd InChi:

InChI=1S/C19H16F3N3O3/c1-10-9-12(28-17-14(19(20,21)22)5-4-8-23-17 )6-7-13(10)15-11(2)16(26)24-18(27)25(15)3/h4-9H,1-3H3,(H,24,26,27)

iuchair InChi:

AKQXQLUNFKDZBN-UHFFFAOYSA-N

Facal-luirg:

1643489-24-0 ；CAS: 1643489-24-0 ； CAS: 1643489-24-0; PF-6649751; PF 6649751; PF6649751; CVL-751; CVL 751; CVL751

Solubility:Soluble ann an DMSO

Stòradh:Tioram, dorcha agus aig 0 - 4 C airson geàrr-ùine (làithean gu seachdainean) no -20 C airson ùine fhada (mìosan gu bliadhnaichean).

Tuairisgeul:

Tha Tavapadon, ris an canar cuideachd PF-6649751 agus CVL-751, na agonist gabhadair dopamine pàirt. Faodaidh e a bhith feumail ann a bhith a’ làimhseachadh galar Pharkinson agus Alzheimer’s.

Targaid: Luchd-gabhail pàirt dopamine d1 / d5