CAT # | Ainm toraidh | Tuairisgeul |
CPD101235 | diABZI STING agonist-1 trihydrochloride | diABZI STING agonist-1 (trihydrochloride) na bhrosnachadh roghnach de agonist gabhadair ginean interferon (STING), le EC50s de 130, 186 nM airson daonna agus luchag, fa leth. |
CPD101234 | diABZI STING agonist-1 (Tautomerism) | diABZI STING agonist-1 Tha Tautomerism (compound 3) na bhrosnachadh roghnach de agonist receptor interferon genes (STING), le EC50s de 130, 186 nM airson daonna agus luchag, fa leth. |
CPD101233 | diABZI STING agonist-1 | Tha diABZI STING agonist-1 na bhrosnachadh roghnach de agonist receptor interferon genes (STING), le EC50s de 130, 186 nM airson daonna agus luchag, fa leth. |
CPD101232 | Sting agonist-4 | Tha STING agonist-4 na neach-brosnachaidh de neach-gabhail gabhadair Interferon Genes (STING) le seasmhach bacaidh follaiseach (IC50) de 20 nM. Tha STING agonist-4 na stuth stèidhichte air amidobenzimidazole (ABZI) co-cheangailte ri co-chothromachd gus ABZIs (diABZIs) ceangailte a chruthachadh le ceangal nas fheàrr ri STING agus gnìomh ceallach. |
CPD101231 | Sting agonist-3 | Tha STING agonist-3, air a thoirt a-mach à patent WO2017175147A1 (eisimpleir 10), na agonist STING beag-molecule roghnach agus neo-nucleotide le pEC50 agus pIC50 de 7.5 agus 9.5, fa leth. Tha buaidh seasmhach an-aghaidh tumhair aig STING agonist-3 agus comas air leth airson làimhseachadh aillse a leasachadh |