Momelotinib; CTY387

Ainm Ceimigeach:

N-(cyanomethyl)-4-(2-((4-morpholinophenyl)amino)pyrimidin-4-yl)benzamide

Còd SMILES:

O=C(NCC#N)C1=CC=C(C2=NC(NC3=CC=C(N4CCOCC4)C=C3)=NC=C2)C=C1

Còd InChi:

InChI=1S/C23H22N6O2/c24-10-12-25-22(30)18-3-1-17(2-4-18)21-9-11-26-23(28-21)2 7-19-5-7-20(8-6-19)29-13-15-31-16-14-29/h1-9,11H,12-16H2,(H,25,30)(H, 26,27,28)

iuchair InChi:

ZVHNDZWQTBEVRY-UHFFAOYSA-N

Facal-luirg:

1056634-68-4, CAS:1056634-68-4 ； CAS: 1056634-68-4 ；Momelotinib

Solubility:Soluble ann an DMSO, DMF

Stòradh:Tioram, dorcha agus aig 0 - 4 C airson geàrr-ùine (làithean gu seachdainean) no -20 C airson ùine fhada (mìosan gu bliadhnaichean).

Tuairisgeul:

Tha Momelotinib (CYT387) na neach-dìon farpaiseach JAK1 / JAK2 de ATP.

Targaid: JAK1/JAK2