Lirafugratinib; RLY-4008

Ainm Ceimigeach:

N-[4-(4-amino-5-{3-fluoro-4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin- 6-il) phenyl]-2-methylprop-2-enamide

Còd SMILES:

C=C(C)C(NC1=CC=C(C2=C(C3=CC=C(OC4=NC=CC(C)=N4)C(F)=C3)C5=C(N)N= CN=C5N2C)C=C1)=O

Còd InChi:

InChI=1S/C28H24FN7O2/c1-15(2)27(37)35-19-8-5-17(6-9-19)24-22(23-25(30)32-14-33-26( 23) 36(24)4)18-7-10-21(20(29)13-18)38-28-31-12-11-16(3)34-28/h5-14H,1H2,2- 4H3, (H,35,37)(H2,30,32,33)

iuchair InChi:

XOQVZSSDIQQUGO-UHFFFAOYSA-N

Facal-luirg:

2549174-42-5 ； CAS: 2549174-42-5 ； CAS: 2549174-42-5 ； Lirafugratinib; RLY-4008; RLY 4008; RLY4008

Solubility: 

Stòradh:Tioram, dorcha agus aig 0 - 4 C airson geàrr-ùine (làithean gu seachdainean) no -20 C airson ùine fhada (mìosan gu bliadhnaichean).

Tuairisgeul:

Tha Lirafugratinib (RLY-4008) na neach-dìon FGFR2 a tha gnìomhach gu beòil, neo-atharrachail agus air leth roghnach.

Targaid: FGFR2