Ifebemtinib, BI 853520

Ainm Ceimigeach:

4-[[4-[(2,3-Dihydro-2-methyl-3-oxo-1H-isoindol-4-yl)oxy]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2-fluoro- 5-methoxy-N-(1-methyl-4-piperidinyl) benzamide

Còd SMILES:

O=C(NC1CCN(C)CC1)C2=CC(OC)=C(NC3=NC=C(C(F)(F)F)C(OC4=CC=CC(CN5C)=C4C5=O))= N3) C = C2F

Còd InChi:

InChI=1S/C28H28F4N6O4/c1-37-9-7-16(8-10-37)34-24(39)17-11-22(41-3)20(12-19(17)29)35- 27-33-13-18(28(30,3 1)32)25(36-27)42-21-6-4-5-15-14-38(2)26(40)23(15)21/h4-6,11-13,16H,7- 10,14H2,1-3H3,(H,34,39)(H,33,35,36)

iuchair InChi:

ULMMVBPTWVRPSI-UHFFAOYSA-N

Facal-luirg:

1227948-82-4 ； CAS: 1227948-82-4 ； CAS: 1227948-82-4 ；Ifebemtinib；BI 853520

Solubility:Soluble ann an DMSO, chan ann ann an uisge

Stòradh:0 - 4 C airson geàrr-ùine (làithean gu seachdainean), no -20 C airson ùine fhada (mìosan).

Tuairisgeul:

Tha Ifebemtinib (BI 853520) na neach-dìon làidir de kinase adhesion fòcas (FAK) le gnìomhachd beòil.

Targaid: Neach-bacadh làidir FAK