BN104

Ainm Ceimigeach:

(2- (6- (2- (4-cyclopropylpyrimidin-5-yl)-4-fluorophenoxy)) -1,2,4-triazin-5-il)-2,7-diazaspiro[3.5]nonan-7-yl ((1S,3aR,6aS)-octahydrocyclopenta[c]pyrrol-1-il)methanone

Còd SMILES:

[H][C@@]12CCC[C@]1(H])[C@H](NC2)C(=O)N3CCC4(CN(C4)C5=C(OC6=CC=C(F)) C=C6C7=CN=CN=C7C8CC8)N=NC=N5)CC3

Còd InChi:

1S/C31H35FN8O2/c32-21-6-7-25(23(12-21)24-14-33-17-35-26(24)19-4-5-19)42-29-28(36- 18-37-38-29)40-15-31(16-40)8-10-39(11-9-31)30(41)27-22-3-1-2-20(22)13- 34-27/h6-7,12,14,17-20,22,27,34H,1-5,8-11,13,15-16H2/t20-,22-,27-/m0/s1

iuchair InChi:

XDXAYPYOHXUEAM-CLHVYKLBSA-N

Facal-luirg:

2938995-50-5 ； CAS: 2938995-50-5 CAS: 2938995-50-5 ；BN-104

Solubility: 

Stòradh:Tioram, dorcha agus aig 0 -4 C airson geàrr-ùine (làithean gu seachdainean) no -20 C airson ùine fhada (mìosan gu bliadhnaichean)

Tuairisgeul:

Faodaidh BN-104 (BNM-1192) bacadh a chur air eadar-obrachadh Menin MLL agus faodar a chleachdadh ann an rannsachadh aillse, leithid leucemia myeloid acute.

Targaid: Menin-MLL