BI-3812

Ainm Ceimigeach:

1-(5-Chloro-4-((8-methoxy-1-methyl-3-(2-(methylamino)-2-oxoethoxy)-2-oxo-1,2-dihydroquinolin-6-yl)amino)pyrimidin -2-il) -N, N-dimethylpiperidine-4-carboxamide

Còd SMILES:

O=C(C1CCN(C2=NC=C(Cl)C(NC3=CC4=C(N(C)C)C(OCC(NC)=O)=C4)=O)C(OC)=C3) =N2)CC1)N(C)C

Còd InChi:

InChI=1S/C26H32ClN7O5/c1-28-21(35)14-39-20-11-16-10-17(12-19(38-5)22(16)33(4)25(20)37) 30-23-18( 27) 13-29-26(31-23)34-8-6-15(7-9-34)24(36)32(2)3/h10-13,15H,6-9,14H2,1- 5H3,(H,28,35)(H,29,30,31)

iuchair InChi:

XCGYXEVLQIIEJH-UHFFFAOYSA-N

Facal-luirg:

BI-3812; BI 3812; BI3812

Solubility: 

Stòradh: 

Tuairisgeul:

Tha BI-3812 na neach-bacadh làidir air eadar-obrachadh fearann ​​​​BTB / POZ de BCL6 le grunn cho-repressors. Bidh e ag obair le bhith a’ cur bacadh air cruthachadh iom-fhillte BCL6 :: Co-repressor.

Targaid: BCL6