Unesbulin frije basis, PTC596

Gemyske namme:

5-fluor-2-(6-fluor-2-methyl-1H-benzo[d]imidazol-1-yl)-N4-(4-(trifluormethyl)fenyl)pyrimidine-4,6-diamine

SMILES Koade:

NC1=C(F)C(NC2=CC=C(C(F)(F)F)C=C2)=NC(N3C(C)=NC4=CC=C(F)C=C34)=N1

InChi Koade:

InChI=1S/C19H13F5N6/c1-9-26-13-7-4-11(20)8-14(13)30(9)18-28-16(25)15( 21)17(29-18)27-12-5-2-10(3-6-12)19(22,23)24/h2-8H,1H3,(H3,25,27,28,29)

InChi Key:

TWLWOOPCEXYVBE-UHFFFAOYSA-N

Keyword:

1610964-64-1; CAS: 1610964-64-1; CAS: 1610964-64-1; Unesbulin frije basis; PTC596; PTC-596; PTC 596

Oplosberens:Oplosber yn DMSO

Opslach:Droog, tsjuster en by 0 - 4 C foar koarte termyn (dagen oant wiken) of -20 C foar lange termyn (moannen oant jierren).

Beskriuwing:

Unesbulin (PTC596) is in mûnling effektive en selektive B-sel-spesifike Moroni-mûs leukemy firus yntegraasje site 1 (BMI-1) inhibitor.

Doel: BMI-1