PRT 543; C220; PRMT5 inhibitor

Gemyske namme:

(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-[(R)-(4-chlorfenyl)-hydroxymethyl]oxolane-3,4 -diol

SMILES Koade:

O[C@H]1[C@H](N2C=CC3=C(N)N=CN=C32)O[C@H]([C@@H](C4=CC=C(Cl)C =C4)O)[C@H]1O

InChi Koade:

InChI=1S/C17H17ClN4O4/c18-9-3-1-8(2-4-9)11(23)14-12(24)13(25)17(26-14)22-6-5-10- 15 (19)20-7-21-16(10)22/h1-7,11-14,17,23-25H,(H2,19,20,21)/t11-,12+,13-,14- ,17-/m1/s1

InChi Key:

ITEKIFMGFZAFPM-QFRSUPTLSA-N

Keyword:

1989620-03-2；CAS：1989620-03-2；CAS:1989620-03-2；PRT-543; PRT543; PRT 543; C220; PRMT5-ynhibitor; PRMT5 inhibitor C220

Oplosberens: 

Opslach:Droog, tsjuster en by 0 - 4 C foar koarte termyn (dagen oant wiken) of -20 C foar lange termyn (moannen oant jierren).

Beskriuwing:

PRMT5-IN-35 (Compound 87) is in effektive selektive en oraal aktive PRMT5-ynhibitor.

Doel: PRMT5