ARS-1620
Produkt Detail
Produkt Tags
| Pak Grutte | Beskikberens | Priis (USD) |
| 100mg | In stock | 800 |
| 500mg | In stock | 1500 |
| 1g | In stock | 2000 |
| Mear maten | Get Quotes | Get Quotes |
Gemyske namme:
(S)-1-(4-(6-chloor-8-fluor-7-(2-fluor-6-hydroxyfenyl)kinazolin-4-yl)piperazin-1-yl)prop-2-en-1-on
SMILES Koade:
C=CC(=O)N1CCN(CC1)C2=C3C=C(C(=C4C(=O)C=CC=C4F)C(=C3NC=N2)F)Cl
InChi Koade:
InChI=1S/C21H17ClF2N4O2/c1-2-16(30)27-6-8-28(9-7-27)21-12-10-13(22)17(19(24)20(12)25- 11-26-21)18-14(23)4-3-5-15(18)29/h2-5,10-11,29H,1,6-9H2
InChi Key:
QIQWMIZVWVSRAS-UHFFFAOYSA-N
Keyword:
ARS-1620, KRAS G12C, NSCLC, ARS1620, ARS 1620, KRASG12C, 1698055-85-4
Oplosberens:Oplosber yn DMSO
Opslach:0 - 4 °C foar koarte termyn (dagen oant wiken), of -20 °C foar lange termyn (moannen)
Beskriuwing:
ARS-1620 is in prodrug ûntworpen fan ARS-853, dat is in krêftige en selektive S-IIP G12C-ynhibitor. ARS-1620 wurdt ferwachte in terapeutyske strategy te wêzen foar p.G12C KRAS mutante kankers.
Doel: KRAS (K-Ras G12C)
