5,6-Difluoro-thalidomide;AUN97411
Allinich foar wittenskiplik ûndersyk, net foar pasjinten.
Produkt Detail
Produkt Tags
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Gemyske namme:
2-(2,6-Dioxopiperidin-3-yl)-5,6-difluoro-2,3-dihydro-1H-isoindole-1,3-dion
SMILES Koade:
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=C(F)C(F)=C3)=O
InChi Koade:
InChI=1S/C13H8F2N2O4/c14-7-3-5-6(4-8(7)15)13(21)17(12(5)20)9-1-2-10(18)16-11( 9)19/h3-4,9H,1-2H2,(H,16,18,19)
InChi Key:
AGHXYRKTAZEQQW-UHFFFAOYSA-N
Keyword:
1496997-41-1; CAS: 1496997-41-1; CAS: 1496997-41-1; 5,6-Difluoro-thalidomide; AUN97411; AUN-97411; AUN 97411
Oplosberens:
Opslach:Droog, tsjuster en by 0 - 4 C foar koarte termyn (dagen oant wiken) of -20 C foar lange termyn (moannen oant jierren).
Beskriuwing:
Thalidomide-5,6-F is in cereblonligand basearre op Thalidomide dat CRBN-proteinen kin rekrutearje.
Doel: cereblon
![(4'S,5'R)-6"-chlor-4'-(2-chloro-3-fluoropyridin-4-yl)-4,4-dimethyl-2"-oxodispiro[cyclohexane-1,2'- pyrrolidine-3',3''-indoline]-5'-carboxylic acid](http://www.caerulumpharm.com/uploads/20240815142152.jpg)
