NX-2127

Nome chimicu:

3-((4-(1-(((3R)-1-(2-(2,6-diossopiperidin-3-il)-1,3-diossoisoindolin-5-il)pirrolidin-3-il)metil) piperidin-4-il)fenil)ammino)-5-(piperidin-1-il)pirazin-2-carboxammide

Codice SMILES:

O=C(C1=NC=C(N2CCCCC2)N=C1NC3=CC=C(C4CCN(C[C@@H]5CN(C6=CC7=C(C(N(C(CC8)C(NC8=O)) )=O)C7=O)=O)C=C6)CC5)CC4)C=C3)N

Codice InChi:

InChI=1S/C39H45N9O5/c40-35(50)34-36(43-32(21-41-34)46-15-2-1-3-16-46)42-27-6-4-25( 5-7-27)26-13-17-45(18-14-26)22-24-12-19-47(23-24)28-8-9-29-30(20-28)39( 53)48(38(29)52)31-10-11-33(49)44-37(31)51/h4-9,20-21,24,26,31H,1-3,10-19, 22-23H2,(H2,40,50)(H,42,43)(H,44,49,51)/t24-,31?/m1/s1

InChi Key:

XLWJWCMQMBVNSG-LZDHLTRGSA-N

Keyword:

2416131-46-7；CAS:2416131-46-7；CAS:2416131-46-7；NX-2127；NX2127；NX 2127

Solubilità: 

Conservazione:Seccu, scuru è à 0 - 4 C per cortu termini (ghjorni à settimane) o -20 C per longu (mesi à anni).

Descrizzione:

NX-2127 hè un inhibitore BTK orale efficace.

Target: BTK