ARD-2128

Nome chimicu:

N-((1r,3r)-3-(3-cloro-4-cianofenossi)-2,2,4,4-tetrametilciclobutil)-4-(4-((1-(2-(2,6-diossopiperidina)) -3-il)-1,3-diossoisoindolin-5-il)piperidin-4-il)metil)piperazin-1-il)benzamide

Codice SMILES:

O=C(C1C=CC(N2CCN(CC3CCN(C4C=CC5C(=O)N(C(=O)C=5C=4)C4C(=O)NC(=O)CC4)CC3)CC2)=CC =1)N[C@@H]1C(C)(C)[C@@H](OC2C=C(Cl)C(C#N)=CC=2)C1(C)C

Codice InChi:

InChI=1S/C45H50ClN7O6/c1-44(2)42(45(3,4)43(44)59-32-11-7-29(25-47)35(46)24-32)49-38( 55)28-5-8-30(9-6-28)52-21-19-50(20-22-52)26-27-15-17-51(18-16-27)31-10- 12-33-34(23-31)41(58)53(40(33)57)36-13-14-37(54)48-39(36)56/h5-12,23-24,27, 36,42-43H,13-22,26H2,1-4H3,(H,49,55)(H,48,54,56)/t36?,42-,43-

InChi Key:

BWDWHHAZFQBJQL-JABICJEXSA-N

Keyword:

2222111-87-5；CAS:2222111-87-5；CAS:2222111-87-5；ARD-2128；ARD 2128；ARD2128

Solubilità: 

Conservazione: 

Descrizzione:

Target: Agente degradante efficace di u receptore di androgeni protac (AR).