Ziftomenib;KO539

Igama:(S)-4-Methyl-5-((4-((2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno(2,3-d)pyrimidin-4-yl)amino)piperidin -1-yl)methyl)-1-(2-(4-(methylsulfonyl)piperazin-1-yl)propyl)-1H-indole-2-carbonitrile

Inombolo yekhathalogi:I-CPD113642

Inombolo ye-CAS:2134675-36-6

Isisindo se-Molecular:717.87

I-Chemical Formula:C33 H42 F3 N9 O2 S2

Olocwaningo lwesayensi kuphela, hhayi lweziguli.

Thumela i-imeyili kithi Landa njenge-PDF

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Usayizi Wephakethe	Ukutholakala	Intengo (USD)
0.1G	Kukhona kusitoki	650
0.5G	Kukhona kusitoki	970
1G	Kukhona kusitoki	1350

Igama Lekhemikhali:

(S)-4-Methyl-5-((4-((2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno(2,3-d)pyrimidin-4-yl)amino)piperidin -1-yl)methyl)-1-(2-(4-(methylsulfonyl)piperazin-1-yl)propyl)-1H-indole-2-carbonitrile

Ikhodi ye-SMILES:

N#CC(N1C[C@@H](N2CCN(S(=O)(C)=O)CC2)C)=CC3=C1C=CC(CN4CCC(NC5=C(C=C(CC(F)) (F)F)S6)C6=NC(NC)=N5)CC4)=C3C

Ikhodi ye-InChi:

I-InChI=1S/C33H42F3N9O2S2/c1-21(43-11-13-44(14-12-43)49(4,46)47) 19-45-25(18-37)15-27-22(2)23(5-6-29(27)45)20-42-9-7-24(8-10-42 )39-30-28-16-26(17-33(34,35)36)48-31(28)41-32(38-3)40-30/h5-6, 15-16,21,24H,7-14,17,19-20H2,1-4H3,(H2,38,39,40,41)/t21-/m0/s1

I-InChi Key:

BGGALFIXXQOTPY-NRFANRHFSA-N

Igama elingukhiye:

2134675-36-6;CAS:2134675-36-6;CAS:2134675-36-6;Ziftomenib; I-KO539; KO 539; KO-539

Ukunyibilika:Kuzonqunywa

Isitoreji:Eyomile, emnyama futhi ku-0 - 4 C isikhathi esifushane (izinsuku ukuya emavikini) noma -20 C isikhathi eside (izinyanga kuya eminyakeni).

Incazelo:

I-Ziftomenib (KO-539) iyisivimbeli sokusebenzisana kwe-menin MLL nomsebenzi womlomo.

Ithagethi: i-menin-MLL

Okwedlule: 4,6-dichloro-5-fluoro-2-Methanesulfonyl-pyriMidine

Olandelayo: I-N-Methyl-5-(piperazin-1-yl)picolinamide hydrochloride