I-Vardenafil

Igama Lekhemikhali:

2-(2-ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propyl-3,5,6,7-tetrahydro-4H-5l4-imidazo[1, 5-a][1,3,5]triazin-4-one

Ikhodi ye-SMILES:

O=C(NC(C1=CC(S(=O)(N2CCN(CC)CC2)=O)=CC=C1OCC)=N3)[N]4(C)C3=CN(CCC)C4

Ikhodi ye-InChi:

I-InChI=1S/C23H35N6O4S/c1-5-10-27-16-21-24-22(25-23(30)29(21,4)17-27)19-15-18(8-9-20( 19) 33-7-3)34(31,32)28-13-11-26(6-2)12-14-28/h8-9,15-16H,5-7,10-14,17H2,1- 4H3,(H,24,25,30)

I-InChi Key:

UWRWYSQUBZFWPU-UHFFFAOYSA-N

Igama elingukhiye:

Vardenafil, Levitra, Staxyn, Vivanza, BAY 38-9456, BAY-38-9456, BAY38-9456, 224785-90-4

Ukunyibilika:I-Soluble ku-DMSO

Isitoreji:0 - 4°C isikhathi esifushane (izinsuku ukuya emavikini), noma -20°C isikhathi eside (izinyanga)

Incazelo:

I-Vardenafil, eyaziwa nangokuthi i-BAY 38-9456, iyi-PDE5 inhibitor esetshenziselwa ukwelapha ukungasebenzi kahle kwe-erectile. Izinkomba ze-Vardenafil kanye ne-contra-indication zifana nezinye i-PDE5 inhibitors; ihlobene eduze nomsebenzi ku-sildenafil citrate (Viagra) ne-tadalafil (Cialis). Umehluko phakathi kwe-molecule ye-vardenafil ne-sildenafil citrate indawo ye-athomu ye-nitrogen kanye noshintsho lweqembu le-methyl leringi ye-sildenafil ye-piperazine ibe yiqembu le-ethyl. I-Tadalafil ihluke ngokwesakhiwo kukho kokubili i-sildenafil ne-vardenafil. Isikhathi esifushane esisebenza kahle sikaVardenafil siqhathaniswa nesika-sildenafil.

Ithagethi: PDE5