I-MDK7526 HCl

Igama Lekhemikhali:

(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride

Ikhodi ye-SMILES:

O=C([C@H]1N(C([C@@H](N)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C (C3=C(C)N=CS3)C=C2.[H]Cl

Ikhodi ye-InChi:

I-InChI=1S/C22H30N4O3S.ClH/c1-13-18(30-12-25-13)15-7-5-14(6-8-15)10-24-20(28)17-9-16( 27)11-26(17)21(29)19(23)22(2,3)4;/h5-8,12,16-17,19,27H,9-11,23H2,1-4H3,( H,24,28);1H/t16-,17+,19-;/m1./s1

I-InChi Key:

JYRTWGCWUBURGU-MSSRUXLCSA-N

Igama elingukhiye:

I-MDK7526 HCl, i-protein degrader 1 hydrochloride, MDK7526, MDK-7526, MDK 7526, 1448189-80-7

Ukunyibilika:I-Soluble ku-DMSO

Isitoreji:0 - 4°C isikhathi esifushane (izinsuku ukuya emavikini), noma -20°C isikhathi eside (izinyanga).

Incazelo:

I-MDK7526, eyaziwa nangokuthi i-VHL Ligand 1; I-protein degrader 1, iyi-protein degrader enamandla futhi ekhethayo. I-MDK7526 ine-CAS#1448297-52-6, usawoti wayo we-HCl une-CAS#1448189-80-7. I-MDK7526 ingaba wusizo ekonakaleni okuhlosiwe kwe-androgen receptor. I-MDK7526 ibopha i-androgen receptor ngendlela yokuthi i-androgen receptor ibekwe eduze ne-ubiquitin ligase ukuze isebenze i-degrdn. (kanye nokuvimbela) kwe-androgen receptor.

Ithagethi: I-Androgen Receptor