LOXO-305;LY 3527727;Pirtobrutinib

Igama Lekhemikhali:

(S)-5-amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan-2-yl)-1H-pyrazole-4- i-carboxamide

Ikhodi ye-SMILES:

O=C(C1=C(N)N([C@@H](C)C(F)(F)F)N=C1C2=CC=C(CNC(C3=CC(F)=CC=C3OC )=O)C=C2)N

Ikhodi ye-InChi:

I-InChI=1S/C22H21F4N5O3/c1-11(22(24,25)26)31-19(27)17(20(28)32)18(30-31)13-5-3-12(4-6- 13)10 -29-21(33)15-9-14(23)7-8-16(15)34-2/h3-9,11H,10,27H2,1-2H3,(H2,28,32)(H ,29,33)/t11-/m0/s1

I-InChi Key:

FWZAWAUZXYCBKZ-NSHDSACASA-N

Igama elingukhiye:

2101700-15-4;CAS:2101700-15-4;CAS:2101700-15-4;LOXO-305;LOXO 305;LOXO305;LY 3527727;LY-3527727;LY3527727b;

Ukunyibilika: 

Isitoreji:Eyomile, emnyama futhi ku-0 - 4 C isikhathi esifushane (izinsuku ukuya emavikini) noma -20 C isikhathi eside (izinyanga kuya eminyakeni).

Incazelo:

I-Pirtobrutinib (LOXO-305) iyisivimbeli se-BTK sesizukulwane esilandelayo esikhetha kakhulu futhi esingahlangani esingavimbela ukuguqulwa okuhlukile kwe-BTK C481.

Ithagethi: BTK