NDI-101150

Igama Lekhemikhali:

(S)-7-((6-((dimethylamino)methyl)-5-(tetrahydrofuran-3-yl)pyridin-2-yl)amino)-4-(7-fluoroimidazo[1,2-a]pyridin- 3-yl) isoindolin-1-one

Ikhodi ye-SMILES:

O=C1NCC2=C(C3=CN=C4N3C=CC(F)=C4)C=CC(NC5=CC=C([C@@]6([H])COCC6)C(CN(C)C) =N5)=C21

Ikhodi ye-InChi:

I-InChI=1S/C27H27FN6O2/c1-33(2)14-22-18(16-8-10-36-15-16)4-6-24(32-22)31-21-5-3-19( 20-12-30-27(35)26(20)21)23-13-29-25-11-17(28)7-9-34(23)25/h3-7,9,11,13, 16H,8,10,12,14-15H2,1-2H3,(H,30,35)(H,31,32)/t16-/m1/s1

I-InChi Key:

QOMXZMCZISKNPU-MRXNPFEDSA-N

Igama elingukhiye:

2628486-22-4;CAS:2628486-22-4;CAS:2628486-22-4;NDI-101150; NDI 101150; NDI101150

Ukunyibilika: 

Isitoreji:Yomile, emnyama futhi ku-0 -4 C isikhathi esifushane (izinsuku ukuya emavikini) noma -20 C isikhathi eside (izinyanga kuya eminyakeni).

Incazelo:

I-NDI-101150 iyi-inhibitor enamandla futhi ekhethiwe ye-HPK1 (i-hematopoietic progenitor cell kinase 1).

Ithagethi: HPK1