I-Lirafugratinib; I-RLY-4008

Igama Lekhemikhali:

N-[4-(4-amino-5-{3-fluoro-4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7-methyl-7H-pyrrolo[2,3-d]pyrimidin- 6-yl)phenyl] -2-methylprop-2-enamide

Ikhodi ye-SMILES:

C=C(C)C(NC1=CC=C(C2=C(C3=CC=C(OC4=NC=CC(C)=N4)C(F)=C3)C5=C(N)N= CN=C5N2C)C=C1)=O

Ikhodi ye-InChi:

I-InChI=1S/C28H24FN7O2/c1-15(2)27(37)35-19-8-5-17(6-9-19)24-22(23-25(30)32-14-33-26( 23)36(24)4)18-7-10-21(20(29)13-18)38-28-31-12-11-16(3)34-28/h5-14H,1H2,2- 4H3,(H,35,37)(H2,30,32,33)

I-InChi Key:

XOQVZSSDIQQUGO-UHFFFAOYSA-N

Igama elingukhiye:

2549174-42-5;CAS:2549174-42-5;CAS:2549174-42-5;Lirafugratinib; I-RLY-4008; I-RLY 4008; RLY4008

Ukunyibilika: 

Isitoreji:Eyomile, emnyama futhi ku-0 - 4 C isikhathi esifushane (izinsuku ukuya emavikini) noma -20 C isikhathi eside (izinyanga kuya eminyakeni).

Incazelo:

I-Lirafugratinib (RLY-4008) iyisivimbeli esisebenza ngomlomo, esingenakuhlehliswa, futhi esikhetha kakhulu i-FGFR2.

Ithagethi: FGFR2