I-DEL-22379
Imininingwane Yomkhiqizo
Omaka bomkhiqizo
Usayizi Wephakethe | Ukutholakala | Intengo (USD) |
100mg | Kukhona kusitoki | 350 |
250mg | Kukhona kusitoki | 600 |
1g | Kukhona kusitoki | 1200 |
Osayizi abengeziwe | Thola Izingcaphuno | Thola Izingcaphuno |
Igama Lekhemikhali:
(Z)-N-(3-((5-methoxy-1H-indol-3-yl)methylene)-2-oxoindolin-5-yl)-3-(piperidin-1-yl)propanamide
Ikhodi ye-SMILES:
O=C(NC1=CC2=C(NC(/C2=C/C3=CNC4=C3C=C(OC)C=C4)=O)C=C1)CCN5CCCCC5
Ikhodi ye-InChi:
I-InChI=1S/C26H28N4O3/c1-33-19-6-8-23-20(15-19)17(16-27-23)13-22-21-14-18(5-7-24(21) 29-26(22) 32)28-25(31)9-12-30-10-3-2-4-11-30/h5-8,13-16,27H,2-4,9-12H2,1H3,(H,28 ,31)(H,29,32)/b22-13+
I-InChi Key:
I-INQUULXCZAKMS-LPYMAVHISA-N
Igama elingukhiye:
DEL-22379, DEL22379, DEL 22379, 181223-80-3
Ukunyibilika:I-Soluble ku-DMSO
Isitoreji:0 - 4°C isikhathi esifushane (izinsuku ukuya emavikini), noma -20°C isikhathi eside (izinyanga)
Incazelo:
I-DEL-22379 iyi-ERK Dimerization inhibitor enamandla futhi ekhethayo. I-DEL-22379 ivimbela i-ERK Dimerization ngaphandle kokuthinta i-ERK phosphorylation, ivimbela i-tumorigenesis eqhutshwa i-RAS-ERK pathway oncogenes. Cishe i-50% yezifo ezibulalayo zabantu zibonisa izimpawu ze-RAS-ERK ezingalawulwa; ukuyivimbela kuyisu elivumelekile lokungenelela kwe-antineoplastic.
Ithagethi: ERK