Ziftomenib;KO539

Orukọ Kemikali:

(S) -4-Methyl-5- ((4- (2- (methylamino)) -6- (2,2,2-trifluoroethyl) thieno (2,3-d) pyrimidin-4-yl) amino) piperidin -1-yl) methyl) -1- (2- (4- (methylsulfonyl) piperazin-1-yl) propyl) -1H-indole-2-carbonitrile

KỌỌDỌ SMILES:

N#CC(N1C[C@@H](N2CCN(S(=O)(C)=O)CC2)C=CC3=C1C=CC(CN4CCC(NC5=C(C=C(CC(F)) (F)F)S6)C6=NC(NC)=N5)CC4)=C3C

Koodu InChi:

InChi=1S/C33H42F3N9O2S2/c1-21(43-11-13-44(14-12-43)49(4,46)47)19-45-25(18-37)15-27-22(2) 23 (5-6-29 (27)45)20-42-9-7-24 (8-10-42)39-30-28-16-26(17-33(34,35)36)48- 31 (28) 41-32 (38-3) 40-30 / h5-6,15-16,21,24H,7-14,17,19-20H2,1-4H3,(H2,38,39,40 ,41)/t21-/m0/s1

Bọtini InChi:

BGGALFIXXQOTPY-NRFANRHFSA-N

Koko-ọrọ:

2134675-36-6;CAS:2134675-36-6;CAS:2134675-36-6;Ziftomenib; KO539; KO 539; KO-539

Solubility:Lati pinnu

Ibi ipamọ:Gbẹ, dudu ati ni 0 - 4 C fun igba kukuru (ọjọ si awọn ọsẹ) tabi -20 C fun igba pipẹ (osu si ọdun).

Apejuwe:

Ziftomenib (KO-539) jẹ oludena ti ibaraenisepo menin MLL pẹlu iṣẹ ṣiṣe ẹnu.

Àkọlé: menin-MLL