Obicetrapib;AMG-899;TA-8995

Orukọ Kemikali:

4-((2- ((3,5-bis (trifluoromethyl)) benzyl) ((2R,4S) -1- (ethoxycarbonyl) -2-ethyl-6- (trifluoromethyl) -1,2,3,4-tetrahydroquinolin -4-yl)amino)pyrimidin-5-yl)oxy) butanoic acid

KỌỌDỌ SMILES:

O=C(O)CCCOC1=CN=C(N(CC2=CC(F)(F)F)=CC(C(F)(F)F)=C2)[C@H]3C[C @@H](CC)N(C(OCC)=O)C4=C3C=C(C(F)(F)F)C=C4)N=C1

Koodu InChi:

InChi=1S/C32H31F9N4O5/c1-3-22-14-26(24-13-19(30(33,34)35)7-8- 25(24)45(22)29(48)49-4-2)44(28-42-15-23(16-43-28)50-9-5-6-27( 46)47)17-18-10-20(31(36,37)38)12-21 (11-18)32(39,40)41/h7-8,10 -13,15-16,22,26H,3-6,9,14,17H2,1-2H3,(H,46,47)/t22-,26+/m1/s1

Bọtini InChi:

NRWORBQAOQVYBJ-GJZUVCINSA-N

Koko-ọrọ:

866399-87-3;CAS:866399-87-3;CAS:866399-87-3;Obiketrapib; AMG-899; AMG 899; AMG899; TA-8995; TA8995; TA 8995; DEZ-001; DEZ 001; DEZ001

Solubility:Tiotuka ni DMSO

Ibi ipamọ:Gbẹ, dudu ati ni 0 - 4 C fun igba kukuru (ọjọ si awọn ọsẹ) tabi -20 C fun igba pipẹ (osu si ọdun).

Apejuwe:

Obicetrapib, ti a tun mọ ni AMG-899, TA-8995, ati DEX-001, jẹ amuaradagba gbigbe ester cholesteryl (CETP).

afojusun: CETP