Divarasib, GDC 6036

Divarasib, GDC 6036
  • Orukọ:1-((S) -4- (7- ((R)) -6-amino-4-methyl-3- (trifluoromethyl) pyridin-2-yl)-6-chloro-8-fluoro-2-((((( S) -1-methylpyrrolidin-2-yl) methoxy) quinazolin-4-yl) -3-methylpiperazin-1-yl) prop-2-en-1-ọkan
  • Katalogi No.CPD112857
  • CAS No.:2417987-45-0
  • Ìwúwo Molikula:622.06
  • Fọọmu Kemikali:C29 H32 Cl F4 N7 O2
  • Fun iwadi ijinle sayensi nikan, kii ṣe fun awọn alaisan.

    Alaye ọja

    ọja Tags

    Iwọn Pack Wiwa Iye owo (USD)
    0.1G O wa 550
    0.5G O wa 860
    1G O wa 1250

    Orukọ Kemikali:

    1-((S) -4- (7- ((R)) -6-amino-4-methyl-3- (trifluoromethyl) pyridin-2-yl)-6-chloro-8-fluoro-2-((((( S) -1-methylpyrrolidin-2-yl) methoxy) quinazolin-4-yl) -3-methylpiperazin-1-yl) prop-2-en-1-ọkan

    KỌỌDỌ SMILES:

    NC1=N[C@]([C@]2=C(C=C3C(N=C(N=C3N4[C@H](CN(CC4)C(C=C)=O)C)OC[ C@H]5N(CCC5)C=C2F)Cl)=C(C(C)=C1)C(F)(F)F

    Koodu InChi:

    InChi=1S/C29H32ClF4N7O2/c1-5-21(42)40-9-10-41(16(3)13-40)27-18-12-19(30)22(26-23(29(32, 33)34)15 (2)11-20 (35)36-26)24(31)25(18)37-28(38-27)43-14-17-7-6-8-39(17)4/h5,11-12,16-17H ,1,6-10,13-14H2,2-4H3,(H2,35,36)

    Bọtini InChi:

    ZRBPIAWWRPFDPY-UHFFFAOYSA-N

    Koko-ọrọ:

    2417987-45-0;CAS:2417987-45-0;CAS:2417987-45-0;Divarasib;GDC 6036

    Solubility:SolubilityLati pinnu

    Ibi ipamọ:Gbẹ, dudu ati ni 0 - 4 C fun igba kukuru (ọjọ si awọn ọsẹ) tabi -20 C fun igba pipẹ (osu si ọdun).

    Apejuwe:

    Divarasib (GDC-6036) jẹ onidalẹkun KRAS G12C pẹlu bioavailability ẹnu ati yiyan.

    Àfojúsùn: KRAS G12C onidalẹkun




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