BN104

Orukọ Kemikali:

(2- (6- (2- (4-cyclopropylpyrimidin-5-yl)) -4-fluorophenoxy -1,2,4-triazin-5-yl) -2,7-diazaspiro [3.5] nonan-7-yl ) ((1S,3aR,6aS) -octahydrocyclopenta [c] pyrrol-1-yl) methanone

KỌỌDỌ SMILES:

[H][C@@]12CCC[C@] 1([H])[C@H](NC2)C(=O)N3CCC4(CN(C4)C5=C(OC6=CC=C(F) C=C6C7=CN=CN=C7C8CC8)N=NC=N5)CC3

Koodu InChi:

1S/C31H35FN8O2/c32-21-6-7-25(23(12-21)24-14-33-17-35-26(24)19-4-5-19)42-29-28(36- 18-37-38-29)40-15-31(16-40)8-1 0-39 (11-9-31)30 (41)27-22-3-1-2-20 (22)13-34-27/h6-7,12,14,17-20,22,27, 34H,1-5,8-11,13,15-16H2/t20-,22-,27-/m0/s1

Bọtini InChi:

XDXAYPYOHXUEAM-CLHVYKLBSA-N

Koko-ọrọ:

2938995-50-5;CAS:2938995-50-5;CAS:2938995-50-5;BN-104：BN104：BN 104

Solubility: 

Ibi ipamọ:Gbẹ, dudu ati ni 0 -4 C fun igba kukuru (ọjọ si awọn ọsẹ) tabi -20 C fun igba pipẹ (awọn oṣu si ọdun)

Apejuwe:

BN-104 (BNM-1192) le ṣe idiwọ ibaraenisepo Menin MLL ati pe o le ṣee lo ninu iwadii alakan, gẹgẹbi aisan lukimia myeloid nla.

afojusun: Menin-MLL