BI-3812

Orukọ Kemikali:

1- (5-Chloro-4- ((8-methoxy-1-methyl-3- (2- (methylamino))-2-oxoethoxy) -2-oxo-1,2-dihydroquinolin-6-yl) amino) pyrimidin -2-yl) -N, N-dimethylpiperidine-4-carboxamide

KỌỌDỌ SMILES:

O=C(C1CCN(C2=NC=C(Cl)C(NC3=CC4=C(N(C)C(C(OCC(NC)=O)=O)=C4)=O)C(OC)=C3) =N2)CC1)N(C)C

Koodu InChi:

InChi=1S/C26H32ClN7O5/c1-28-21(35)14-39-20-11-16-10-17(12-19(38-5)22(16)33(4)25(20)37) 30-23-18 (27) 13-29-26 (31-23)34-8-6-15 (7-9-34)24 (36)32 (2) 3/h10-13,15H,6- 9,14H2,1-5H3,(H,28,35)(H,29,30,31)

Bọtini InChi:

XCGYXEVLQIIEJH-UHFFFAOYSA-N

Koko-ọrọ:

BI-3812; BI 3812; BI3812

Solubility: 

Ibi ipamọ: 

Apejuwe:

BI-3812 jẹ oludena ti o lagbara ti ibaraenisepo ti BTB / POZ domain ti BCL6 pẹlu ọpọlọpọ awọn apanilẹrin. O ṣiṣẹ nipa didi BCL6 :: Co-repressor eka Ibiyi.

afojusun: BCL6