iZidesamtinib; I-NVL-520

Igama leMchiza:

(6R)-22-ethyl-54-fluoro-42,6-dimethyl-22H,42 H-7-oxa1(3,5)-pyridina-2(3,4)-pyrazola-4(4,5)- [1,2,3]triazola5(1,2)-benzenacycloheptaphan-16-amine

Ikhowudi yoncumo:

FC1=CC([C@](OC2=C(N=CC3=C2)N)(C)[H])=C(C=C1)C4=NN(N=C4CC5=C3N(N=C5)CC )C

Ikhowudi ye-InChi:

InChI=1S/C22H22FN7O/c1-4-30-21-13(11-26-30)7-18-20(28-29(3)27-18)16-6-5-15(23)9- 17(16)12(2)31-19-8-14(21)10-25-22(19)24/h5-6,8-12H,4,7H2,1-3H3,(H2,24,25 )/t12-/m1/s1

Isitshixo se-InChi:

DTWUUAFTYSMNQX-GFCCVEGCSA-N

Igama elingundoqo:

2739829-00-4;CAS:2739829-00-4;CAS:2739829-00-4;Zidesamtinib; I-NVL-520; I-NVL520; I-NVL 520

Ukunyibilika: 

Ugcino:Yomile, emnyama kunye ne-0 - 4 C kwixesha elifutshane (iintsuku ukuya kwiiveki) okanye -20 C ixesha elide (iinyanga ukuya kwiminyaka).

Inkcazo:

I-Zidesamtinib (i-NVL-520) yinto esebenzayo, ekhethiweyo, esebenza ngomlomo, kunye ne-blood-brain barrier permeable ROS1 fusion kunye nokumelana nokuguqulwa kwe-inhibitor.

Ithagethi: IROS1