I-Sitagliptin

I-Sitagliptin
  • Igama:I-Sitagliptin
  • Inombolo yekhathalogu:CPDA0100
  • Inombolo yeCAS:654671-77-9(Sitagliptin Phosphate Monohydrate); 654671-78-0 (Sitagliptin Phosphate); 486460-32-6(isiseko sasimahla)
  • Ubunzima beMolekyuli:407.31
  • Ifomula yemichiza:I-C16H15F6N5O
  • Kuphando lwenzululwazi kuphela, hayi izigulane.

    Iinkcukacha zeMveliso

    Iithegi zeMveliso

    Ubungakanani bePakethi Ubukho Ixabiso (USD)

    Igama leMchiza:

    I-Sitagliptin (INN; ichongiwe ngaphambili njenge-MK-0431 kwaye ithengiswe phantsi kwegama lorhwebo i-Januvia) i-antihyperglycemic yomlomo (i-anti-diabetic drug) yeklasi ye-dipeptidyl peptidase-4 (DPP-4) inhibitor.

    Ikhowudi yoncumo:

    O=C(N1CC2=NN=C(C(F)(F)F)N2CC1)C[C@H](N)CC3=CC(F)=C(F)C=C3F.O=P(O )(O)O.[H]O[H]

    Ikhowudi ye-InChi:

    InChI=1S/C16H15F6N5O.H3O4P.H2O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27- 13(7- 26)24-25-15(27)16(20,21)22;1-5(2,3)4;/h4,6,9H,1-3,5,7,23H2;(H3,1, 2,3,4);1H2/t9-;;/m1../s1

    Isitshixo se-InChi:

    GQPYTJVDPQTBQC-KLQYNRQASA-N

    Igama elingundoqo:

    Sitagliptin,Sitagliptin phosphate,Januvia,Glactiv,ONO-5435, MK-0431, L-000224715, 654671-77-9,654671-78-0, 486460-32-6

    Ukunyibilika:Inyibilika kwi-DMSO

    Ugcino:0 - 4°C ixesha elifutshane (iintsuku ukuya kwiiveki), okanye -20°C ixesha elide (iinyanga).

    Inkcazo:

    I-Sitagliptin (INN; ichongiwe ngaphambili njenge-MK-0431 kwaye ithengiswe phantsi kwegama lorhwebo i-Januvia) i-antihyperglycemic yomlomo (i-anti-diabetic drug) yeklasi ye-dipeptidyl peptidase-4 (DPP-4) inhibitor. Yaphuhliswa kwaye ithengiswa nguMerck & Co. Le mveliso ye-enzyme-inhibiting drug isetyenziswe yodwa okanye idibene namanye ama-antihyperglycemic agents omlomo (afana ne-metformin okanye i-thiazolidinedione) yonyango lwe-diabetes mellitus uhlobo lwe-2. Inzuzo yeli yeza liyeza. iziphumo ebezingalindelekanga ezisezantsi (umzekelo, ukuncipha kwe-hypoglycemia, ubunzima obuncinci) kulawulo lwamaxabiso eswekile yegazi. I-Exenatide (i-Byetta) nayo isebenza ngempembelelo yayo kwinkqubo ye-incretin.

    Ithagethi: DPP-4


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