| CAT # | Haryt ady | Düşündiriş |
| CPD100391 | SHP394 | |
| CPD100390 | SHP389 (mugt esas) | |
| CPD3242 | RMC-4550 | RMC-4550 güýçli we saýlama SHP2 inhibitorydyr. RMC-4550, SHP2-iň çiş biologiýasynda, hem in vitro, hem-de gemrijilerdäki wivo roluny öwrenmek üçin ýokary hilli gural birleşmesi hökmünde kesgitlenildi. SHP2 birleşdiriji signal düwünidir we SHP2-iň gadagan edilmegi, RAS-MAPK ýolundaky ýokary akym (RTK bilen dolandyrylýan) we aşaky akym (RAS-GTP bagly) mutasiýalary nyşana almakda täsirli. |
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