DEL-22379
Lintlha tsa Sehlahisoa
Li-tag tsa Sehlahisoa
| Boholo ba Pakete | Ho fumaneha | Theko (USD) |
| 100mg | E teng thepeng e teng ka lebenkeleng | 350 |
| 250mg | E teng thepeng e teng ka lebenkeleng | 600 |
| 1g | E teng thepeng e teng ka lebenkeleng | 1200 |
| Boholo bo Eketsehileng | Fumana Litlhaloso | Fumana Litlhaloso |
Lebitso la lik'hemik'hale:
(Z)-N-(3-((5-methoxy-1H-indol-3-yl)methylene)-2-oxoindolin-5-yl)-3-(piperidin-1-yl)propanamide
SMILES Khouto:
O=C(NC1=CC2=C(NC(/C2=C/C3=CNC4=C3C=C(OC)C=C4)=O)C=C1)CCN5CCCCC5
Khoutu ea InChi:
InChI=1S/C26H28N4O3/c1-33-19-6-8-23-20(15-19)17(16-27-23)13-22-21-14-18(5-7-24(21) 29-26 (22) 32)28-25(31)9-12-30-10-3-2-4-11-30/h5-8,13-16,27H,2-4,9-12H2,1H3,(H,28 ,31)(H,29,32)/b22-13+
InChi Key:
INQUULXCZAKMS-LPYMAVHISA-N
Keyword:
DEL-22379, DEL22379, DEL 22379, 181223-80-3
Sollubility:E qhibiliha ka DMSO
Polokelo:0 - 4 ° C bakeng sa nako e khutšoanyane (matsatsi ho isa libeke), kapa -20 ° C bakeng sa nako e telele (likhoeli)
Tlhaloso:
DEL-22379 ke e matla le e khethang ERK Dimerization inhibitor. DEL-22379 e thibela ERK Dimerization ntle le ho ama phosphorylation ea ERK, e thibela tumorigenesis e tsamaisoang ke RAS-ERK pathway oncogenes. Hoo e ka bang karolo ea 50 lekholong ea makhopho a batho a bontša pontšo e sa laoleheng ea RAS-ERK; ho e thibela ke leano le nepahetseng bakeng sa ho kenella ha antineoplastic.
Sepheo: ERK
