BAY-299
Lintlha tsa Sehlahisoa
Li-tag tsa Sehlahisoa
| Boholo ba Pakete | Ho fumaneha | Theko (USD) |
| 100mg | E teng thepeng e teng ka lebenkeleng | 500 |
| 500mg | E teng thepeng e teng ka lebenkeleng | 800 |
| 1g | E teng thepeng e teng ka lebenkeleng | 1200 |
| Boholo bo Eketsehileng | Fumana Litlhaloso | Fumana Litlhaloso |
Lebitso la lik'hemik'hale:
2-(2,3-dihydro-1,3,6-trimethyl-2-oxo-1H-benzimidazol-5-yl)-6-(3-hydroxypropyl)-1H-benz[de]isoquinoline-1,3( 2H) -dione
SMILES Khouto:
OCCCC1=CC=C(C(N2C3=C(C)C=C(N(C)C(N4C)=O)C4=C3)=O)C5=C1C=CC=C5C2=O
Khoutu ea InChi:
InChI=1S/C25H23N3O4/c1-14-12-20-21(27(3)25(32)26(20)2)13-19(14)28-23(30)17-8-4-7- 16-15(6-5-11-29)9-10-18(22(16)17)24(28)31/h4,7-10,12-13,29H,5-6,11H2,1- 3H3
InChi Key:
OFWWWKUCDUISA-UHFFFAOYSA-N
Keyword:
BAY-299, BAY 299, BAY299, 2080306-23-4
Sollubility:E qhibiliha ka DMSO
Polokelo:0 - 4 ° C bakeng sa nako e khutšoanyane (matsatsi ho isa libeke), kapa -20 ° C bakeng sa nako e telele (likhoeli).
Tlhaloso:
BAY-299 ke inhibitor e matla le e khethang ea protheine ea lelapa ea bromodomain le PHD e nang le menoana (BRPF) BRD1 (IC50 = 6 nM), e tsejoang hape e le BRPF2, le bromodomain ea bobeli ea transcription initiation factor TFIID subunits 1 (TAF1; IC50) = 13 nM).1 BAY-299 e > e khetha ka makhetlo a 30 ho feta BRPF1, BRPF3, BRD9, le ATAD2 'me e > e khetha ka makhetlo a 300 ho feta BRD4.
Sepheo: BRPF