BAY-293

Magaca Kiimikada:

(R) -6,7-dimethoxy-2-methyl-N- (1- (4- (2- ((methylamino)methyl) phenyl) thiophen-2-yl) ethyl) quinazolin-4-amine

Koodhka dhoola cadeynta:

C[C@@H](NC1=C2C=C(OC)C(OC)=CC2=NC(C)=N1)C3=CC(C4=CC=CC=CC=C4CNC)=CS3

Koodhka InChi:

InChi=1S/C25H28N4O2S/c1-15(24-10-18(14-32-24)19-9-7-6-8-17(19)13-26-3)27-25-20-11- 22 (30-4)23 (31-5)12-21 (20)28-16(2)29-25/h6-12,14-15,26H,13H2,1-5H3,(H,27,28 ,29)/t15-/m1/s1

Furaha InChi:

WEGLOYDTDILXDA-OAHLLOKOSA-N

Ereyga muhiimka ah:

BAY-293,BAY 293,BAY293

Xalka: 

Kaydinta: 

Sharaxaad:

BAY-293 waa horjooge awood leh oo SOS1 kaas oo xannibaya firfircoonida RAS iyada oo la carqaladaynayo isdhexgalka RAS-SOS1. BAY-293) waxay si xushmad leh u joojisaa isdhexgalka KRAS-SOS1 ee IC50 ee 21 nM waana baaritaan kiimikaad qiimo leh oo loogu talagalay baaritaannada mustaqbalka.

Bartilmaameedka: SOS1 inhibitor