Ozanimod

Magaca Kiimikada:

(S)-5-(3-(1-(2-hydroxyethyl)amino)-2,3-dihydro-1H-inden-4-yl)-1,2,4-oxadiazol-5-yl)-2 -isopropoxybenzonitrile

Koodhka dhoola cadeynta:

N#CC1=CC(C2=NC(C3=CC=CC4=C3CC[C@@H]4NCCO)=NO2)=CC=C1OC(C)C

Koodhka InChi:

InChi=1S/C23H24N4O3/c1-14(2)29-21-9-6-15(12-16(21)13-24)23-26-22(27-30-23)19-5-3- 4 -18-17(19)7-8-20(18)25-10-11-28/h3-6,9,12,14,20,25,28H,7-8,10-11H2,1-2H3 /t20-/m0/s1

Furaha InChi:

XRVDGNKRPOAQTN-FQEVSTJZSA-N

Ereyga muhiimka ah:

Ozanimod, RPC-1063, RPC1063, RPC 1063, 1306760-87-1

Xalka:Ku milmay DMSO

Kaydinta:0 - 4°C muddo gaaban (maalmo ilaa toddobaadyo), ama -20°C muddo dheer (bilo).

Sharaxaad:

Ozanimod waa doore, habeeyaha afka laga heli karo ee sphingosine-1-phosphate (S1P) reseptors S1P1 iyo SIP5. Waxay keentaa gudaha S1P1, waxay hoos u dhigtaa wareegga B iyo CCR7(+) T lymphocytes, waxayna yaraynaysaa bararka iyo xuduudaha cudurada ee saddexda nooc ee cudurada difaaca jirka.

Ujeedka: S1P