SJ-01

SJ-01
  • Zita:SJ-01
  • Catalog Nhamba:CPD110955
  • Nhamba yeCAS:20069-09-4
  • Molecular Weight:317.34
  • Chemical Formula:C17 H19 N O5
  • Kutsvakurudza kwesayenzi chete, kwete kuvarwere.

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    Chemical Name:

    (E)-1-(3-(3,4,5-trimethoxyphenyl)acryloyl)-5,6-dihydropyridin-2(1H)-imwe

    SMILES Kodhi:

    O=C1C=CCCN1C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)=O

    InChi Code:

    InChI=1S/C17H19NO5/c1-21-13-10-12(11-14(22-2)17(13)23-3)7-8-16(20)18-9-5-4-6- 15(18)19/h4,6-8,10-11H,5,9H2,1-3H3/b8-7+

    InChi Key:

    VABYUUZNAVQNPG-BQYQJAHWSA-N

    Keyword:

    20069-09-4;CAS:20069-09-4;CAS:20069-09-4;Piperlongumine; Piplatine.

    Solubility:Soluble muDMSO

    Kuchengeta:Dry, rima uye pa 0 - 4 C kwenguva pfupi (mazuva kusvika mavhiki) kana -20 C kwenguva refu (mwedzi kusvika kumakore).

    Tsanangudzo:

    Piperlongumine, inozivikanwawo sePiplartine, inonzi biologically active alkaloid/amide kubva mhiripiri, sekubva mhiripiri refu (Piper longum L. - Piperaceae). Mhiripiri yakareba ndeimwe yeanonyanya kushandiswa mumishonga yeAyurvedic, iyo inoshandiswa kurapa zvirwere zvakawanda, kusanganisira mamota. Izvo zvinonzi pharmacological zviitiko zvepiplartine zvinosanganisira cytotoxic, genotoxic, antitumor, antiangiogenic, antimetastatic, antiplatelet aggregation, antinociceptive, anxiolytic, antidepressant, anti-atherosclerotic, antidiabetic, antibacterial, antifungal, leishmanicidal, trypanocisomidal, uye schistomidal zviitiko. Pakati peakawanda pharmacological mhedzisiro yepiplatine, iyo anticancer pfuma ndiyo inonyanya kuvimbisa.

    Target: Piperlongumine is alkaloid iyo inhibits shanduko yemyofibroblasts nekuvharira erk1/2 nzira yekusaina.




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