Sildenafil Citrate

Chemical Name:

5-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin- 7-imwe 2-hydroxypropane-1,2,3-tricarboxylate

SMILES Kodhi:

"CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)CC(C(=O)O )C(CC(=O)O)(C(=O)O)O "

InChi Code:

InChI=1S/C22H30N6O4S.C6H8O7/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9- 18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28;7-3(8)1-6(13,5(11)12) 2-4(9)10/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29);13H,1-2H2,(H,7,8)( H,9,10)(H,11,12)

InChi Key:

DEIYFTQMQPDXOT-UHFFFAOYSA-N

Keyword:

Sildenafil Citrate;UK 92480-10;UK-92,480-10; Revatio; VIAGRA;171599-83-0;CAS:171599-83-0;CAS:171599-83-0;

Solubility:Soluble muDMSO

Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi)

Tsanangudzo:

Sildenafil, Citrate is a citrate form of Sildenafil. Sildenafil is selective inhibitor yePDE5 (mhando 5 cGMP phosphodiesterase) iyo inokonzera hydrolysis ye 3',5'-cyclic guanosine monophosphate (cGMP). SePDE5 inhibitor, Sildenafil inonzi inowedzera neuro-, synapto- uye angiogenesis mumakonzo emhando dzesitiroko uye zvakare inonzi inyoro vasodilator. Sildenafil yakaratidzawo kudzivirira indomethacin-induced intestinal ulceration kugadzirwa kuburikidza neNO / cGMP-inotsamira nzira.

Chinangwa: PDE5