S-600918,Sivopixant
Product Detail
Product Tags
Pack Saizi | Kuwanikwa | Mutengo (USD) |
Chemical Name:
(2S)-3-[(4E)-3-[(4-chlorophenyl)methyl]-2,6-dioxo-4-({4-[(pyridin-2-yl)oxy]phenyl}imino)-1 ,3,5-triazinan-1-yl] -2-methylpropanoic acid
SMILES Kodhi:
O=C(O)[C@@H](C)CN1C(N(CC2=CC=C(Cl)C=C2)/C(NC1=O)=N/C3=CC=C(OC4=NC =CC=C4)C=C3)=O
InChi Code:
InChI=1S/C25H22ClN5O5/c1-16(22(32)33)14-31-24(34)29-23(30(25(31)35)15-17-5-7-18(26)8- 6-17)28-1 9-9-11-20(12-10-19)36-21-4-2-3-13-27-21/h2-13,16H,14-15H2,1H3,(H,32,33)( H,28,29,34)/t16-/m0/s1
InChi Key:
SKZQFKBIJUXXCG-INIZCTEOSA-N
Keyword:
2414285-40-6; CAS:2414285-40-6; CAS:2414285-40-6; Sivopixant; S-600918; S 600918; S600918
Solubility:Soluble muDMSO
Kuchengeta:Yakaoma, yakasviba uye pa 0 - 4 C kwenguva pfupi (mazuva kusvika kumavhiki) kana -20 C kwenguva refu (mwedzi kusvika kumakore)
Tsanangudzo:
Sivopixant, inozivikanwawo seS-600918, inosarudza P2X3 receptor antagonist (P2X3 IC50, 4.2 nM; P2X2 / 3 IC50, 1100 nM). Sivopixant yakaratidza yakasimba analgesic effect mu rat partial sciatic nerve ligation model (Seltzer model) yeallodynia (ED50, 0.4 mg / kg).
Chinangwa: Sarudza P2X3 receptor antagonist