Resmetirom
Product Detail
Product Tags
Pack Saizi | Kuwanikwa | Mutengo (USD) |
Chemical Name:
Resmetirom
SMILES Kodhi:
N#CC1=NN(C2=CC(Cl)=C(OC(C=C3C(C)C)=NNC3=O)C(Cl)=C2)C(NC1=O)=O
InChi Code:
InChI=1S/C17H12Cl2N6O4/c1-7(2)9-5-13(22-23-15(9)26)29-14-10(18)3-8(4-11( 14)19)25-17(28)21-16(27)12(6-20)24-25/h3-5,7H,1-2H3,(H,23,26)(H,21,27, 28)
InChi Key:
FDBYIYFVSAHJLY-UHFFFAOYSA-N
Keyword:
MGL-3196; MGL 3196; VIA 3196; VIA-3196; Resmetirom
Solubility:Soluble muDMSO, kwete mumvura
Kuchengeta:0 - 4 C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 C kwenguva refu (mwedzi)
Tsanangudzo:
Resmetirom, inozivikanwawo seMGL-3196, ine simba uye inosarudza zvakanyanya thyroid hormone receptor β agonist mumakiriniki miedzo yekurapa dyslipidemia. Migumisiro inobatsira yethyroid hormone (TH) pane lipid mazinga anonyanya kukonzerwa nekuita kwayo pathyroid hormone receptor β (THR-β) muchiropa, asi migumisiro yakaipa, kusanganisira migumisiro yemwoyo, inopindirana nethyroid hormone receptor α (THR). -α).
Chinangwa: THR-β