IACS-010759
Product Detail
Product Tags
| Pack Saizi | Kuwanikwa | Mutengo (USD) |
| 100mg | Mudura | 300 |
| 500mg | Mudura | 800 |
| 1g | Mudura | 1200 |
| Mamwe Saizi | Wana MaQuotes | Wana MaQuotes |
Chemical Name:
5-(5-methyl-1-(3-(4-(methylsulfonyl)piperidin-1-yl)benzyl)-1H-1,2,4-triazol-3-yl)-3-(4-(trifluoromethoxy) phenyl) -1,2,4-oxadiazole
SMILES Kodhi:
FC(F)(F)OC1=CC=C(C2=NOC(C3=NN(CC4=CC=CC(N5CCC(S(=O)(C)=O)CC5)=C4)C(C)= N3)=N2)C=C1
InChi Code:
InChI=1S/C25H25F3N6O4S/c1-16-29-23(24-30-22(32-38-24)18-6-8-20(9-7-18)37-25(26,27)28) 31 -34(16)15-17-4-3-5-19(14-17)33-12-10-21(11-13-33)39(2,35)36/h3-9,14,21H ,10-13,15H2,1-2H3
InChi Key:
HWJWNWZJUYCGKV-UHFFFAOYSA-N
Keyword:
IACS-010759, IACS 010759, IACS010759, IACS-10759, IACS 10759, IACS10759, 1570496-34-2, 1807523-99-4
Solubility:Soluble muDMSO
Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi).
Tsanangudzo:
IACS-010759 kana IACS-10759 ine simba uye inosarudza Oxidative Phosphorylation Inhibitor (IC50).<10 nM) ine inogona kuita antineoplastic chiitiko. IACS-010759 inosungira uye inhibits yakaoma I ye elektroni yekutakura cheni (NADH ubiquinone oxidoreductase), nekudaro ichibvisa bundu masero ezvikafu, uye simba, uye inhibiting nucleotide uye amino acid kugadzirwa, iyo induces autophagy, inokonzera bundu sero kufa uye inhibits sero. kuwanda. Mitochondrial complex I, iyo ine hyperactivated mumasero egomarara kuti isangane nekuwedzera kwekuda kwesimba, inoita basa rakakosha mukusimudzira kupararira kwekenza.
Chinangwa: OXPHOS