Etoricoxib

Chemical Name:

5-Chloro-6'-methyl-3--[4-(methylsulfonyl)phenyl] -2,3'-bipyridine

SMILES Kodhi:

O=S(C1=CC=C(C2=CC(Cl)=CN=C2C3=CC=C(C)N=C3)C=C1)(C)=O

InChi Code:

InChI=1S/C18H15ClN2O2S/c1-12-3-4-14(10-20-12)18-17(9-15(19)11-21-18)13-5-7-16(8-6- 13)24(2,22)23/h3-11H,1-2H3

InChi Key:

MNJVRJDLRVPLFE-UHFFFAOYSA-N

Keyword:

Etoricoxib, Arcoxia, L-791456, MK 0663, MK-0663, 202409-33-4

Solubility:Soluble muDMSO

Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi)

Tsanangudzo:

Etoricoxib is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) ine antipyretic, analgesic, uye inogona antiineoplastic properties. Etoricoxib inonyanya kusunga uye inhibits enzyme cyclooxygenase-2 (COX-2), zvichiita kuti inhibition yekushandurwa kwearachidonic acid kuita prostaglandin. Kuvharirwa kweCOX-2 kunogona kukonzera apoptosis uye kurambidza bundu masero kuwanda uye angiogenesis.

Chinangwa: COX-2