SJ-01

SJ-01
  • Igoa:SJ-01
  • Numera fa'amaumauga:CPD110955
  • Numera CAS:20069-09-4
  • Molecular Weight:317.34
  • Fua fa'atatau ole vaila'au:C17 H19 N O5
  • Mo na'o su'esu'ega fa'asaienisi, ae le mo gasegase.

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    Igoa vaila'au:

    (E)-1-(3-(3,4,5-trimethoxyphenyl)acryloyl)-5,6-dihydropyridin-2(1H)-tasi

    SMILES Code:

    O=C1C=CCCN1C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)=O

    InChi Code:

    InChI=1S/C17H19NO5/c1-21-13-10-12(11-14(22-2)17(13)23-3)7-8-16(20)18-9-5-4-6- 15(18)19/h4,6-8,10-11H,5,9H2,1-3H3/b8-7+

    InChi Key:

    VABYUUZNAVQNPG-BQYQJAHWSA-N

    upu autu:

    20069-09-4;CAS:20069-09-4;CAS:20069-09-4;Piperlongumine; Piplartine.

    Solubility:Solu i le DMSO

    Teuina:Mago, pogisa ma i le 0 - 4 C mo taimi pupuu (aso i vaiaso) po'o le -20 C mo taimi uumi (masina i tausaga).

    Fa'amatalaga:

    Piperlongumine , e lauiloa foi o Piplartine, o se alkaloid/amide olaola olaola mai pepa, e pei o pepa umi (Piper longum L. - Piperaceae). O le pepa umi o se tasi o mea sili ona faʻaaogaina i vailaʻau Ayurvedic, lea e faʻaaogaina e togafitia ai le tele o faʻamaʻi, e aofia ai le tuma. O gaioiga faʻafomaʻi lipotia o le piplartine e aofia ai le cytotoxic, genotoxic, antitumor, antiangiogenic, antimetastatic, antiplatelet aggregation, antinociceptive, anxiolytic, antidepressant, anti-atherosclerotic, antidiabetic, antibacterial, antifungal, leishmanicidal, trypanocidal, ma gaoioiga faʻamalosi. Faatasi ai ma le tele o aʻafiaga faʻafomaʻi o le piplartine, o lona anticancer meatotino e sili ona faʻamoemoeina.

    Manulauti: Piperlongumine ose alkaloid e taofia ai le suiga o myofibroblasts e ala i le taofia o le erk1/2 ala faailoilo.




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