STING

PUSI # Igoa Oloa Fa'amatalaga
CPD101235 diABZI STING agonist-1 trihydrochloride o le diABZI STING agonist-1 (trihydrochloride) o se faʻamalosi filifilia o kenera interferon (STING), faʻatasi ai ma EC50s o le 130, 186 nM mo le tagata ma le isumu.
CPD101234 diABZI STING agonist-1 (Tautomerism) diABZI STING agonist-1 Tautomerism (compound 3) o se mea e fa'aosofia ai le filifilia o genes interferon (STING) receptor agonist, fa'atasi ai ma EC50s o le 130, 186 nM mo tagata ma isumu.
CPD101233 diABZI STING agonist-1 o le diABZI STING agonist-1 o se fa'aoso fa'aoso filifilia o genes interferon (STING) receptor agonist, fa'atasi ai ma EC50s o le 130, 186 nM mo le tagata ma le isumu.
CPD101232 STING agonist-4 STING agonist-4 o se stimulator o Interferon Genes (STING) receptor agonist faʻatasi ai ma se faʻalavelave faʻafuaseʻi (IC50) o le 20 nM. STING agonist-4 o se lua fa'atusa fa'atatau amidobenzimidazole (ABZI) fa'avae fa'avae e fausia ai ABZIs feso'ota'i (diABZIs) fa'atasi ai ma le fa'aleleia atili o le fusifusia i le STING ma le telefoni feavea'i.
CPD101231 STING agonist-3 STING agonist-3, maua mai le pateni WO2017175147A1 (faʻataʻitaʻiga 10), o se faʻataʻitaʻiga STING agonist laiti ma le nucleotide faʻatasi ma le pEC50 ma le pIC50 o le 7.5 ma le 9.5, i le faasologa. O le STING agonist-3 e iai sona aafiaga umi e tetee atu ai i le pumo ma e tele lona malosi e faaleleia atili ai togafitiga o le kanesa
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